::
When you attempt this transaction, do you have any other crypto wallets or applications open? Specifically, do you have anything else that your Ledger is connected to, open while you try this send transaction with your NFT? If so, this is likely what is causing the connectivity error.
Usually this exact error is only thrown if the user „denies“ or „rejects“ a transaction with the physical Ledger, such that it prompted you to confirm and you chose to „reject“ or „deny“ the transaction.
If you connect your Ledger to MetaMask as a [hardware-connected wallet](https://www.ledger.com/academy/security/the-safest-way-to-use-metamask) (via the accounts tab), are you able to send your NFT with success?
In the instance that there are any issues occurring within Ledger Live, testing out this transaction with MetaMask would be a great way to discern whether the error is being thrown by the Ledger Live software, or if something else may be causing it.