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When you connect your ledger to MM and use „connect hardware wallet“, regardless of the MM seed, you will always get access to the same accounts, which are addresses derived from your ledger seed (not derived from your MM seed).
Those accounts are marked „ledger“ or „hardware“ in MM, and those are the only accounts that are secured by your ledger device.
As long as you only use those accounts, you are fine, and you can stake and unstake your tokens safely, and you will have access to those accounts from any computer (and any MM using any MM seed), as long as you have your ledger device.