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If you’re going this route, then the issue is that Ledger misrepresented the product as having certain characteristics (highest security because the keys physically can’t leave the device) which proved to be false. The product is not as described, or defective as a cold wallet.
People’s success with this approach might vary based on how long ago the purchase was made, how many purchases they’ve disputed in the past, etc, but all the major CC companies should be able to process chargebacks based on this line of reasoning…
AMEX – C31 Goods/Services Not As Described
Discover – RM Cardholder Disputes Quality of Goods or Services
Visa – 13.3 Not as Described or Defective Merchandise/ Services